An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Mucosal melanocytic macules Pigmented Lesions Springer Nature Link Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Melanotan (MT) II Melanocortin Receptor Agonist MedChemExpress