Glucose metabolism begins with its transport into cells via GLUT transporters, where it is phosphorylated to glucose 6 phosphate (Glucose 6 P). This molecule can enter various pathways, including the pentose phosphate pathway or hexosamine biosynthesis. HMP also known as the Pentose phosphate pathway. Consists of two irreversible oxidative rxs followed by a series of reversible biochemistry Why is the Pentose Phosphate Pathway so active in erythrocytes? Biology Stack Exchange Quantitative Importance of the Pentose Phosphate Pathway Determined by Incorporation of 13C from [2 13C] and [3 13C]Glucose into TCA Cycle Intermediates and Neurotransmitter Amino Acids in Functionally Intact Neurons Eva M F Pentose Phosphate Cycle an overview ScienceDirect Topics